Â鶹´«Ã½Ó³»­

Â鶹´«Ã½Ó³»­

Explore the latest content from across our publications
Join The Â鶹´«Ã½Ó³»­

Log In

Forgot Password?
Create New Account

Loading... please wait

Abstract Details

Quality of Life in African American and White Parkinson’s Disease Patients
Movement Disorders
Movement Disorders Posters (7:00 AM-5:00 PM)
055

To determine the phenotype of African American (AA) and white patients with Parkinson’s disease (PD) at the Rush University Medical Center (RUMC) Movement Disorders Clinic.

The literature describing PD and impact on quality of life (QoL) or other non-motor features is less robust in AA compared to white patients. This study focused on motor, non-motor and other QoL measures in AA PD patients compared to whites.  

Patients with PD in a tertiary clinic were approached to participate in a study examining PD in AA and white patients. After consent, demographics were collected and a battery of tests were performed, including the MDS-UPDRS Part III, NIH Toolbox measures, Patient Health Expectation Questionnaire, Quality of Life in Neurological Disorders Scale (NeuroQoL), Parkinson’s Disease Questionnaire (PDQ39), Schwab and England, Epworth Sleepiness Scale, and UPSIT smell test.


24 AA PD and 25 white PD patients participated.  47% of the participants were women, average age was 66.9 (+8.18) years old, mean MDS-UPDRS Part III score was 22.2 (+8.87), 74.5% were Hoehn and Yahr stage II (range II to IV); with no differences between groups. AA PD participants had lower scores on the NeuroQoL satisfaction with participation (p=0.03) and NeuroQoL mobility scales (p=0.01), with no difference in NeuroQoL sleep or fatigue scales. Total PDQ39 scores were significantly higher (worse) in the AA participants (p=0.01) with higher scores on the PDQ39 mobility (p=0.01), ADL (p=0.01), cognition (p=0.02), and body discomfort (p=0.04) sections. There were no differences in patient health expectations, Schwab England disability scores, Epworth or UPSIT scores.

Despite similar MDS-UPDRS motor, non-motor scores and overall disability; AA with PD had lower satisfaction with participation in daily activities, increased body discomfort, and reduced patient-reported mobility and cognition compared to white PD patients. Further work is needed to address these disparities. 

 
Authors/Disclosures
Deborah H. Hall, MD, PhD, FÂ鶹´«Ã½Ó³»­ (Rush University)
PRESENTER 		Dr. Hall has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Â鶹´«Ã½Ó³»­. Dr. Hall has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Elsevier - Parkinsonism and Related Disorders. Dr. Hall has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Annals of Neurology. The institution of Dr. Hall has received research support from Parkinson's Foundation. The institution of Dr. Hall has received research support from CHDI. The institution of Dr. Hall has received research support from Uniqure. The institution of Dr. Hall has received research support from NIH.
Sharlet Anderson, PhD (Rush University Medical Center) Dr. Anderson has nothing to disclose.
Glenn T. Stebbins, PhD (Rush University Medical Center) Dr. Stebbins has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Biogen. Dr. Stebbins has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Partners Healthcare System. Dr. Stebbins has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for CHDI. The institution of Dr. Stebbins has received research support from Department of Defense. Dr. Stebbins has received research support from Cleveland Clinic Health Systems. Dr. Stebbins has received personal compensation in the range of $500-$4,999 for serving as a Course Director with MDS.
Lisa L. Barnes, PhD (Rush University Medical Center) Lisa L. Barnes has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Alzheimer's & Dementia. The institution of Lisa L. Barnes has received research support from NIH. Lisa L. Barnes has received personal compensation in the range of $500-$4,999 for serving as a Council member with NACMHD.
Lisa M. Shulman, MD, FÂ鶹´«Ã½Ó³»­ (University of Maryland School of Medicine) The institution of Dr. Shulman has received research support from NIH. Dr. Shulman has received publishing royalties from a publication relating to health care. Dr. Shulman has received publishing royalties from a publication relating to health care.
Meagan O. Bailey, MD (Novant Health Neurology) Dr. Bailey has nothing to disclose.