Abstract Details Title Effects of Low Frequency Repetitive Transcranial Magnetic Stimulation Combined with Language Training on Language Disorder in Children with Cerebral Palsy Topic Child Neurology and Developmental Neurology Presentation(s) Child Neurology and Developmental Neurology Posters (7:00 AM-5:00 PM) Poster/Presentation Number 025 Objective To investigate the clinical effect and mechanism of low frequency repetitive transcranial magnetic stimulation(rTMS) combined with speech training in the treatment of speech retardation in children with cerebral palsy. Background rTMS is a safe and efficacious technique to stimulate specific areas in several neuropsychiatric diseases; However, the application of rTMS in children with cerebral palsy is rarely observed, especially the efficacy of the treatment of speech disorders in children with cerebral palsy is unclear. Design/Methods 92 cases of speech retardation in children with cerebral palsy were randomly divided into combined treatment group (32 cases of speech training with rTMS),speech training group(30 cases of convention speech training) and repetitive transcranial magnetic stimulation group (30 cases of rTMS treatment) . After 6 months of treatment,Chinese language retardation assessment (S-S) was used to evaluate language ability. Results After 6 months of treatment,the total effective rates of combined therapy group,speech training group and repetitive transcranial magnetic stimulation group were 96.8%,83.3% and 80% respectively.The language ability of the combined treatment group was significantly higher than that of the other two groups(P<0.05),and the there was a positive correlation with the time of treatment. Conclusions 1.rTMS stimulation combined with speech training can promote the improvement of speech ability in children with cerebral palsy. 2.rTMS stimulation combined with speech training is more effective than language training or rTMS stimulation alone. 3.rTMS is a painless,non-invasive and safe brain control technique,which can provide a new therapeutic method for the early intervention of speech retardation in children with cerebral palsy. Authors/Disclosures PRESENTER No disclosure on file No disclosure on file