Abstract Details

Title Socioeconomic status and stroke incidence, prevalence, mortality and worldwide burden: an ecological analysis from the Global Burden of Disease Study 2017

Topic Global Health and Neuroepidemiology

Presentation(s) P9 - Poster Session 9 (12:00 PM-1:00 PM)

Poster/Presentation
Number 13-013

Objective To estimate preventable proportion of stroke-related mortality and burden in relation with socioeconomic status (SES).

Background SES is associated with stroke incidence and mortality. Distribution of stroke risk factors is changing worldwide; evidence on these trends is crucial to the allocation of resources for prevention strategies to tackle major modifiable risk factors with the highest impact on stroke burden.

Design/Methods We extracted data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017. We analysed trends in global and SES-specific age-standardised stroke incidence, prevalence, mortality, and disability-adjusted life years (DALYs) lost from 1990 to 2017. We estimated age-standardised attributable risk of stroke mortality associated with common risk factors in low-, low-middle-, upper-middle, and high-income countries. We explored the effect of age and sex on associations of risk factors with stroke mortality from 1990 to 2017.

Results Despite a growth in crude number of stroke events from 1990 to 2017, there has been an 11.3% decrease in age-standardised stroke incidence rate worldwide (150.5, 95% uncertainty interval [UI] 140.3–161.8 per 100,000 in 2017). This has been accompanied by an overall 3.1% increase in age-standardised stroke prevalence rate (1300.6, UI 1229.0–1374.7 in 2017), and a 33.4% decrease in age-standardised stroke mortality rate (80.5, UI 78.9–82.6 in 2017) over the same time period. The rising trends in age-standardised stroke prevalence have been observed only in middle-income countries, despite declining trends in age-standardised stroke incidence and mortality in all income categories since 2005. There has been almost a 34% reduction in stroke death rate (67.8, UI 64.1–71.1 per 100,000 in 2017) attributable to modifiable risk factors, more prominently in wealthier countries.

Conclusions Half of stroke-related deaths are attributable to poor management of modifiable risk factors. SES is still strongly associated with modifiable risk factors and stroke burden, thus screening of people from low SES is crucial.

Authors/Disclosures
PRESENTER	No disclosure on file
Abolfazl Avan, MD, PhD (Work)	Dr. Avan has nothing to disclose.
	No disclosure on file
Mario Di Napoli, MD (ASL Rieti)	Dr. Di Napoli has nothing to disclose.
	No disclosure on file
Reza Behrouz, DO, PhD, F�鶹��ýӳ�� (University of Texas Health Science Center San Antonio)	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
J D. Spence, MD	No disclosure on file

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