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Abstract Details

Congenital Mirror Movements: Case Report
Child Neurology and Developmental Neurology
P8 - Poster Session 8 (8:00 AM-9:00 AM)
5-005

To present a case of congenital mirror movements (CMM).

CMM refers to a condition in which movements on one side of the body results in simultaneous involuntary movement in the opposite side of the body. CMM may be developmental resolving within the first decade of life, or inherited. The main genes involved in CMM disorders are the DCC and RAD51, which are found in approximately 35% of the cases. Mutations in other genes that have not been identified may be responsible for other cases.  
This is a 7 year old girl presenting with mirrored hand movements since the age of 2. When she has movements on one hand they are mirrored by involuntary movements of the other hand. The movements are observed only in her hands. During the last three years there was no improvement in her symptoms. Occupational therapy helped her to suppress these involuntary movements at some extent, as by pressing the left hand on desk top when writing. This has helped her to overcome the embarrassment caused by mirror movements. Her neurological exam is normal. 
She tested negative for DCC and RAD51 genes. Brain MRI was normal. Functional MRI was a limited study, but right handed motor task demonstrated activation of the left-sided central sulcus and the supplementary motor area whereas left-handed motor task demonstrated lesser amplitude of activation of the right central sulcus. Diffusion tension imaging (DTI) with tractography showed intact pyramidal decussation of the corticospinal tracts (CSTs). 

This patient is currently 7 years old, therefore, there is the possibility of resolving her symptoms within a few years. Her neurological exam and brain MRI are normal. Whether the presence of normal tractography showing expected pyramidal crossing of CSTs are helpful to predict full recovery in patients with CMM remains to be determined.

Authors/Disclosures
Nishad Shaheid, MD (OhioHealth Mansfield)
PRESENTER 		Dr. Shaheid has nothing to disclose.
Savitra M. Bandari, MD (JFK Neuroscience Institute) Dr. Bandari has nothing to disclose.
Diosely C. Silveira, MD, PhD, FÂ鶹´«Ã½Ó³»­ (University of Texas Medical Branch) Dr. Silveira has nothing to disclose.
No disclosure on file