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Abstract Details

Study of Clinical, Radiological, and Electroencephalographic Features in Posterior Reversible Encephalopathy Syndrome (PRES)
Cerebrovascular Disease and Interventional Neurology
P2 - Poster Session 2 (8:00 AM-9:00 AM)
4-019

1) To study clinical, MRI findings and EEG abnormalities in PRES 

 2) Follow up findings after 6 weeks.

PRES is a neurological disorder presenting as acute onset myriad symptoms viz headache, disorder of consciousness, visual disturbances, seizures and focal neurological deficits. It frequently develops in pre eclamptic individuals.Typical radiological features include edema of the parieto-occipital lobes and EEG findings include posterior dominant slow waves. Recognising this condition is important as outcome remains favourable.

Patients presenting with headache, seizures, altered conscious status, visual impairment and focal neurological deficits were evaluated.Those who fulfilled MRI features of PRES were recruited in the study. MRI and electroencephalographic (EEG) findings were analysed at the time of admission. Clinical, MRI findings were recorded 6 weeks later. The categorical data was analysed by using Chi-Square test with the help of SPSS Software.

 

We identified 30 patients with PRES. 29 patients were female and 1 patient was male.The most common age group was between 21-25 years and most commonly occurring during post-partum period. The most common clinical presentation was seizure(76.7%).Clinical recovery occurred in all patients within days (mean, 5 ± 2 days).Co-morbid conditions included Eclampsia, Pre-Eclampsia, Hypertension, sepsis and autoimmune disorders. T2/FLAIR Hyperintense lesions across parieto-occipital region on MRI was most common finding  and atypical findings in the form of infarct and haemorrhage were seen in 4 patients.The most common EEG abnormality was posterior dominant slow waves in delta to theta range. All 30 patients improved clinically where as 26 of 30 patients reversed radiologically completely after 6 weeks and 4 remained with sequale of hemorrahage and infarct. 

 

We suggest that PRES may occur in patients with complex systemic conditions.The prognosis of PRES is usually benign.In this study females are more commonly affected and most of them were in a postpartum period and had a good prognosis.

Authors/Disclosures
Mahadevappa Mahadevappa (SS Institute of Medical Sciences and Research Centre)
PRESENTER
No disclosure on file