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Abstract Details

Guideline-Recommended Cancer Screening in Adults with Stroke: A Nationwide Analysis
Cerebrovascular Disease and Interventional Neurology
P14 - Poster Session 14 (8:00 AM-9:00 AM)
4-016

To determine whether stroke survivors are more likely to undergo guideline-recommended cancer screening than the general population.

Stroke can be an early sign of cancer, and 3-10% of patients with stroke are diagnosed with cancer within two years. Several cancer types associated with stroke have established screening paradigms.

We performed a cross-sectional analysis using 2018 data from the CDC Behavioral Risk Factor Surveillance System (BRFSS). The BRFSS is an annual, nationally representative, health-related telephone survey of non-institutionalized Americans. Participants are asked about health conditions and health-related behaviors. In 2018, participants were asked about cancer screening. We included respondents with and without prior stroke. We defined age- and sex-appropriate lung, colorectal, and breast cancer screening based on the United States Preventative Services Task Force (USPSTF) recommendations. Accordingly, for example, lung cancer screening rates were only calculated for respondents ages 55-80 with at least a 30 pack-year smoking history. We used survey-specific methods to calculate screening rates for those with and without prior stroke. We used logistic regression to estimate the odds of screening in stroke survivors, compared to those without stroke, while adjusting for demographics and comorbidities.  

Among 437,436 respondents (51% women), 3.4% reported prior stroke. The rates of USPSTF recommended screening in stroke survivors were 18.3% for lung, 69.9% for colorectal, and 75.3% for breast cancer. After adjusting for demographics and comorbidities, stroke survivors were more likely to undergo breast cancer screening (OR, 1.29; 95% CI, 1.02-1.64) but not lung (OR, 1.11; 95% CI, 0.42-2.90) or colorectal (OR, 1.09; 95% CI, 0.96-1.23) cancer screening.
Stroke survivors are not screened for cancer at a higher rate than the general population, except for breast cancer. Given the robust epidemiological association between stroke and cancer, efforts to optimize rates of standard-of-care cancer screening in stroke survivors are warranted.
Authors/Disclosures
Stephanie Rutrick, MD
PRESENTER
The institution of Dr. Rutrick has received research support from Roche. The institution of Dr. Rutrick has received research support from Lilly. The institution of Dr. Rutrick has received research support from Athira. The institution of Dr. Rutrick has received research support from Abbvie.
Hooman Kamel, MD (Weill Cornell Medical College) Dr. Kamel has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for JAMA Neurology. Dr. Kamel has received personal compensation in the range of $50,000-$99,999 for serving as a Endpoint adjudication committee with Boehringer-Ingelheim.
Babak Navi, MD (Weill Cornell Medical College) Dr. Navi has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Alexion Pharmaceuticals. Dr. Navi has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for MindRhythm Inc. Dr. Navi has received personal compensation in the range of $10,000-$49,999 for serving as an Expert Witness for multiple medicolegal firms.
Neal S. Parikh, MD (Alnylam Pharmaceuticals) Dr. Parikh has received personal compensation for serving as an employee of Alnylam Pharmaceuticals. Dr. Parikh has or had stock in Alnylam Pharmaceuticals.