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Abstract Details

New Onset Sensorimotor Epilepisa Partialis Continua as an initial presentation of Neurocysticercosis
Infectious Disease
P12 - Poster Session 12 (12:00 PM-1:00 PM)
13-001

We discuss a patient who presented with new onset epilepsia partialis continua (EPC) secondary to neurocysticercosis (NCC) with video-based documentation of her clinical episodes.

NCC is the most common cause of acquired epilepsy in developing countries. However, approximately 1,320 to 5,050 new cases of NCC occur every year in the United States. NCC is considered a neglected parasitic infection and it is important for clinicians to be aware of its prevalence, presentation and treatment.

Case report
A 32-year-old female with no significant PMH presented with 2-day history of recurrent episodic involuntary movements of her left upper extremity (LUE) with residual monoparesis. While initially her motor strength recovered inter-episodically, due to increasing frequency of episodes she was unable to use her LUE. During her clinical exam the patient was noted to have an episode of myoclonic jerking of her left shoulder and arm accompanied by LUE paresthesia, followed by worsening distal>proximal LUE weakness which persisted post-ictally. There was no generalization of the movements and no loss or alteration of the patient’s consciousness. MRI brain w/wo contrast showed a large neurocysticercosis cyst anterior to the right central sulcus and smaller calcified cysts in other areas. The patient was diagnosed with EPC and treated with leviteracetam as well as oral steroids prior to beginning cysticidal treatment with albendazole and praziquantel. She required an additional load with lacosamide for breakthrough seizures on day 2 of hospitalization, but subsequently remained seizure free. Her LUE strength recovered completely to her pre-morbid baseline. At her one month follow up the patient continues to do well.
This case is of interest because it is a unique presentation of NCC. Additionally, the patient experienced a successful remission of symptoms with treatment, and so this case may support the future use of leviteracetam and lacosamide in EPC caused by neurocysticercosis.
Authors/Disclosures
Nicole Thomason
PRESENTER 		No disclosure on file
No disclosure on file
Shivika Chandra, MD, FÂ鶹´«Ã½Ó³»­ (University of Texas Health Science Center at Houston) The institution of Dr. Chandra has received research support from American Board of Psychiatry and Neurology Faculty Innovation in Â鶹´«Ã½Ó³»­ Award. The institution of Dr. Chandra has received research support from Michael J Fox Foundation.