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Abstract Details

Screening Predictors of Psychological Reaction to Multiple Sclerosis Diagnosis
Multiple Sclerosis
P10 - Poster Session 10 (5:30 PM-6:30 PM)
9-013
To test whether brief psychological screening at time of multiple sclerosis (MS) diagnosis can identify the need for additional support.
Reaction to MS diagnosis can vary, with some patients being at risk for poor psychological coping mechanisms that can lead to increased stress, reduced self-care, and poorer treatment adherence. Identifying these at-risk patients at time of diagnosis can improve intervention.
We recruited patients at the time of diagnosis to complete a survey at baseline and one year following diagnosis. Questionnaires included the Adverse Childhood Experiences (ACE) inventory, the MS Knowledge Questionnaire (MSKQ), the 36-Item Short Form Health Survey (SF-36), and Self-Management Screening (SeMaS). At follow-up, participants were re-administered the MSKQ, SF-36, and SeMaS scales, along with the Benefit Finding (BF) and Posttraumatic Growth (PTG) inventories to measure reaction to illness. The SeMaS depression and anxiety scales were considered indices of emotional coping.
A total of n=54 participants diagnosed with relapsing remitting MS (median EDSS=1.0, age M=32.15 ±8.4 years) completed the baseline assessment. Among the subset completing the ACE (n=31), it was the single best predictor of both initial (r=.466, R2=.217) and follow-up (r=.413, R2=.171) emotional distress, as well as increased anxiety at follow-up, compared to baseline (r=.389, R2=.152). It was also negatively correlated with subjective experience of self–efficacy at both baseline (r=-.44, p=.013) and follow-up (r=-.509, p=.008). Importantly, measures of PTG and BF were positively correlated with baseline and follow-up measures of self-efficacy, and negatively correlated with depression and anxiety at both time points.
Childhood adversity can be measured using brief screening inventories to identify those patients at increased risk for psychological distress following MS diagnosis. Subjective experience of self-efficacy appears to be an important mediator in patient’s reaction to their illness, and may be reduced in individuals with increased adverse childhood experiences
Authors/Disclosures

PRESENTER 		No disclosure on file
Tehila Eilam-Stock, PhD (NYU Langone Health) Dr. Eilam-Stock has nothing to disclose.
No disclosure on file
No disclosure on file
Tamar Bacon The institution of an immediate family member of Tamar Bacon has received research support from Novartis. The institution of an immediate family member of Tamar Bacon has received research support from Genentech. An immediate family member of Tamar Bacon has received publishing royalties from a publication relating to health care.
Carrie Sammarco Carrie Sammarco has nothing to disclose.
Lisa Laing No disclosure on file
Leigh E. Charvet, PhD (NYU Langone) Dr. Charvet has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Johnson & Johnson. Dr. Charvet has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Springer Healthcare. Dr. Charvet has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for YBrain. Dr. Charvet has stock in Johnson&Johnson.