Abstract Details

Title In 1001 Consecutive Patients Referred to an Academic Neuromuscular Clinic a Range of Neurologic and Non-neurologic Conditions were Diagnosed

Topic Neuromuscular and Clinical Neurophysiology (EMG)

Presentation(s) Neuromuscular and Clinical Neurophysiology (EMG) Posters (7:00 AM-5:00 PM)

Poster/Presentation
Number 138

Objective To determine the spectrum of disorders seen in a tertiary academic neuromuscular (NM) clinic.

Background Neurologists focusing on NM disorders see a wide variety of patients, some having NM disorders, some having non-NM neurologic disease and others having no neurologic diagnosis when all is said and done.

Design/Methods A retrospective analysis was undertaken of 1001 consecutive patients seen by a single neurologist (BES). These patients were referred to the Mayo Clinic Scottsdale NM Clinic over a 5 year period (2015-2020). The patients were divided into three cohorts based on final diagnosis: 1) those found to have neuromuscular diagnoses (n=680), 2) those diagnosed with non-neuromuscular neurologic disorders (n=95), and 3) those found to have non-neurologic conditions (n=256). The numbers do not summate to 1001 in that some subjects appear in both cohorts 1 and 2, having both NM disorders and non-NMD diagnoses.

Results The median ages of cohorts 1, 2 and 3 were 60.5/60/49.5 years respectively, age ranges being 16-91/21-91/17-92 years. The sex ratios (M:F) for the cohorts were 432:248/58:37/92:164 respectively. Referring symptoms/indications for the cohorts were as follow: paresthesia/imbalance 425/64/39, pain 353/32/113, weakness/fatigue 243/26/58, fasciculation/cramps 30/0/4, rhabdomyolysis/elevated CK 11/0/4, widespread varied symptoms 5/7/60, spells 3/2/2, autonomic symptoms 2/1/0, symptoms of non-NM neurologic disease 2/11/0, no symptoms 1/0/0. Major final diagnoses numerically were: polyneuropathy 343/27/0, somatic symptom disorder 149/21/125, small fiber neuropathy 92/0/0, mononeuropathy 50/0/0, radiculopathy 45/3/0, sensory neuropathy 32/2/0, myopathy 32/0/0, motor neuron disease 31/0/0, neuromuscular junction disease 28/0/0, polyradiculoneuropathy 26/0/0, myelopathy 25/58/0, lumbosacral plexus neuropathy 15/0/0, brachial plexopathy 12/0/0, fasciculation/cramps 11/0/3, rhabdomyolysis/CK elevation 9/0/6, non-NM neurologic disease 9/36/0, chronic pain 4/0/64, multifocal motor neuropathy 2/0/0, and paresthesia 2/0/33.

Conclusions

1) Some 67.9% of 1001 NM clinic referrals were found to have a NM diagnosis.

2) Some 9.5% had non-NM neurologic diagnoses.

3) Some 29.5% of the referrals were diagnosed with somatic symptom disorder.

Authors/Disclosures
Benn E. Smith, MD, F�鶹��ýӳ�� PRESENTER	Dr. Smith has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Argenx. Dr. Smith has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for CSP Behring.

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