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Abstract Details

Isolated Neurobrucellosis—a report of 19 cases with some peculiar findings.
Infectious Disease
Infectious Disease Posters (7:00 AM-5:00 PM)
083
Objective: To report various neurological syndromes, CSF findings, imaging and diagnostic methods used in neurobrucellosis patients admitted in our Neurology department over a period of 6 years.
Patients presenting to a Neurology department with chronic infectious illness like meningitis are usually treated as tuberculosis in endemic countries even if diagnostic tests are negative for tuberculosis. Neurobrucellosis has a similar clinical picture and should be differentiated from tuberculosis in view of different treatment regimens and duration.
Case records of patients admitted to our department from August 2014 to May 2020  were searched for neurobrucellosis and data was obtained.
A total of 19 patients were diagnosed as neurobrucellosis over a period of 6 years. Nine patients had chronic meningitis, five had VIII nerve involvement, 1 had optic neuritis, 2 had acute meningitis, 1 had subacute meningitis, 4 had myelopathy, 5 had polyradiculitis and 2 had spondylodiskitis. CSF was abnormal in seventeen patients. Neutrophilic pleocytosis was seen in 12 patients which included nine patients with chronic symptomatology. Brain imaging was abnormal in 3 chronic meningitis patients. One  had diffuse meningeal enhancement, another had hydrocephalus while as third patient had meningeal enhancement with basal exudates and contrast enhancement of bilateral VIII nerve. One of the patients of acute meningitis had hydrocephalus while as other one had bilateral T2/FLAIR hyperintensities with enhancement of leptomeningeal vessels. Elevated antibody titers in serum were seen in 10 patients while as elevated CSF antibody titers were seen in 11 patients. Four patients had elevated antibody titers in both serum and CSF. CSF culture was positive in three patients
Neurobrucellosis is a rare clinical complication of brucellosis but may pose a problem in diagnosis as it can mimic tuberculosis. Involvement of VIII nerve can be a diagnostic clue favoring neurobrucellosis.
Authors/Disclosures
Waseem R. Dar, MD (Shere Kashmir Insitute of Medical Sciences)
PRESENTER 		Dr. Dar has nothing to disclose.
Waseem R. Dar, MD (Shere Kashmir Insitute of Medical Sciences) Dr. Dar has nothing to disclose.
No disclosure on file
No disclosure on file