Â鶹´«Ã½Ó³»­

Â鶹´«Ã½Ó³»­

Explore the latest content from across our publications
Join The Â鶹´«Ã½Ó³»­

Log In

Forgot Password?
Create New Account

Loading... please wait

Abstract Details

Evaluation of medication adherence in an inter-professional epilepsy clinic
Epilepsy/Clinical Neurophysiology (EEG)
Epilepsy/Clinical Neurophysiology (EEG) Posters (7:00 AM-5:00 PM)
082

: The objective of our study is to evaluate the change in medication adherence over time in patients seen at our inter-professional epilepsy clinic in order to help identify characteristics associated with to ASM adherence.

Optimizing medication adherence is especially important in management of patients of with epilepsy (PWE). Non-adherence leads to poor seizure control and thus worse outcomes and quality of life. Studies have shown that patients with epilepsy have an increased risk of death, partly due to higher prevalence of non-adherence to ASM. Furthermore, non-adherence to ASM and thus sub-optimal drug levels have been correlated with higher risk of status epilepticus.
Retrospective chart review was conducted of all veterans with a diagnosis of epilepsy seen in Seizure Clinic at the West LA VA from 7/1/2008 to 6/30/17. This study included patients with diagnosis of focal epilepsy. Exclusion criteria were diagnosis of psychogenic nonepileptic seizures (PNES), absence of evaluation by neurology pharmacist, neurostimulation device, and history of resection surgery. Adherence for ASM was measured by medication possession ratio (MPR) from electronic prescription fill history and patient report. High adherence was determined to be MPR of greater than 75%.

To date, 483 charts were reviewed and 348 patients met inclusion criteria. Analysis of preliminary data shows that approximately 75% of our patients demonstrated high adherence with all of their ASMs. Characteristics related to high adherence will be further analyzed.

Medication adherence is critical for seizure control in PWE. Evaluation of characteristics correlated with positive impact on adherence and identification of potential challenges to adherence will improve clinical outcomes.

Authors/Disclosures
Caroline Kim, Pharmacist (VA Greater Los Angeles Healthcare System)
PRESENTER 		Caroline Kim has nothing to disclose.
Katherine Liao, PharmD (WLA VA Health System) Dr. Liao has nothing to disclose.
Alexander Crossley Mr. Crossley has nothing to disclose.
Brian Toh Brian Toh has nothing to disclose.
Alexander Crossley Mr. Crossley has nothing to disclose.
Sunita Dergalust, PharmD (West LA VA Healthcare Center) Ms. Dergalust has nothing to disclose.
Sunita Dergalust, PharmD (West LA VA Healthcare Center) Ms. Dergalust has nothing to disclose.