Eighty five cases were included. Patients relied more on strategies based on positive reframing, especially acceptance and support strategies, especially instrumental or emotional support. Coping strategies were correlated mainly with age, psychiatric co-morbidities, seizure frequency and stability of the epilepsy. There was a statistically significant correlation between average score of strategies based on positive reframing and social well-being ((r=0,30 ; p=0,004)). Better QOL in its general health component was associated with support-based strategies (r=0,37 ; p=0,01). Improved resilience was associated with better physical and mental QOL, and the use of avoidance-based coping strategies was linked to low resilience. Nearly half of the patients (43.5%) were screened positive for depression at the time of the study.