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Abstract Details

Computed Tomography Perfusion and Magnetic Resonance Imaging in Evaluation of Acute Ischemic Stroke
Cerebrovascular Disease and Interventional Neurology
Cerebrovascular Disease and Interventional Neurology Posters (7:00 AM-5:00 PM)
060
To determine whether the type of advanced imaging, CT perfusion (CTP) or magnetic resonance perfusion (MRP) imaging, used for evaluation of acute ischemic stroke (AIS) impacts clinical outcomes of mechanical thrombectomy (MT).
CTP and MRP are the main advanced imaging modalities utilized in screening patients with AIS for MT. Though MRP has been found to be more sensitive for the diagnosis of AIS, time delays in obtaining MRP may have negative impact on patient outcomes.
We reviewed patients presenting to a comprehensive center from January 2016 through May 2020. All patients included underwent advanced imaging, either CTP or MRP, for evaluation of AIS before being taken for MT. Demographics, clinical characteristics and outcomes including hemorrhagic conversion, radiological recanalization, modified Rankin scale (mRS), and mortality were collected.
There were 61 patients in the CTP group and 106 patients in the MRP group. The two groups did not differ significantly in terms of age, sex, rate of premorbid atrial fibrillation, initial NIHSS, tPA administration, or timing of intervention compared to last-known-well.  Patients who underwent CTP had significantly shorter door-to-imaging times by an average of 47 minutes (p < .01), and trended towards shorter door-to-intervention times by an average of 40 minutes (p =.07).  Favorable 90-day clinical outcomes (mRS ≤ 2) were seen more frequently in patients who had MRP (45%) than CTP (30%), but this was not statistically significant (p = .09). There was no significant difference in percentage of satisfactory radiological outcomes (TICI ≥ 2b), rates of hemorrhagic conversion, or early improvement in NIHSS between the two groups.
The use of CTP shortened both the door-to-imaging and door-to-intervention times, but this did not affect clinical or radiological outcomes. The increased rate of favorable 90-day outcomes within the MRP group merits further investigation.
Authors/Disclosures
Elaine Lu, MD
PRESENTER 		Ms. Lu has nothing to disclose.
Bhageeradh Mulpur, MD (University of Miami/Jackson Memorial Hospital - Vascular Neurology) Dr. Mulpur has nothing to disclose.
Sam S. Handshoe (Norton Healthcare) Dr. Handshoe has nothing to disclose.
Muhammad S. Hussain, MD (Cleveland Clinic) Dr. Hussain has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Cerenovus. Dr. Hussain has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Tiger Medical.