Cerebral venous sinus thrombosis (CVST) is an important cause of stroke in young. There is too little literature on the long-term sequelae of CVST.

Mean age, 33.5±11.4, 52% female. Follow-up after a median of 30 months (range 6-63), 83.6% scored 0–2 on mRS; however, cognitive impairment was seen in 65.8% (MOCA 16.74±5.43), depression in 58.4% (HDRS 9± 4.8) and mean SSQOL 209.7 (±24.9). On univariate analysis, factors associated with a poor functional outcome were low socioeconomic status, diabetes mellitus, hypertension, migraine, malignancy, baseline mass effect, hemiplegia, aphasia and baseline mRS. On multivariate analysis, acute phase mass effect (p=0.042), hemiplegia (p=0.0001) and baseline mRS (p=0.001) had significant association. Low SE status alone was associated with cognitive impairment (p=0.012). Univariate factors associated with depression were puerperium, anaemia, upper middle socioeconomic status, disability and mass effect but only anaemia(p=.031) and mass effect(P=0.04) had multivariate association.

In one of the largest series long term follow up of CVST, though mortality and motor outcome were excellent, long term neuropsychiatric impairment were common.  Acute care and long-term management must have plans to prevent and manage these occult neuropsychiatric deficits.