Abstract Details

Title The Mobile Toolbox (MBT): A Completely Remote Platform for Cognitive Research

Topic Aging, Dementia, and Behavioral Neurology

Presentation(s) Aging and Dementia Posters (7:00 AM-5:00 PM)

Poster/Presentation
Number 065

Objective We introduce the Mobile Toolbox Battery (MTB), a library of cognitive assessments for at-home smartphone administration. It is designed for safe, remote, and effective data collection, particularly among older adults.

Background Cognitive Impairment (CI) is estimated to affect more than 16 million people (Centers for Disease Control and Prevention, 2011). About 5.8 million Americans are living with dementia, severe cognitive decline, most often due to Alzheimer’s Disease, with a projected increase to 13.8 million people aged 65 and older by 2050 (Alzheimer’s Association, 2020). There is a clear need for early detection of cognitive impairment due to neurodegenerative brain disease as well as to differentiate it from more benign, age- associated changes. However, there are currently few sensitive assessment tools to meet this need and fewer yet that can be easily and widely deployed across the lifespan, in different research settings, and with diverse participants.

Design/Methods MTB provides a complete research platform for app creation, study management, and data collection for participants 20-85 years old. Available for both iOS and Android devices, we envision the MTB being used in fully remote or follow-up remote studies. The initial core tests within MTB were designed to measure comparable cognitive skills to those in the well-established NIH Toolbox Cognition Battery, often utilized for in-person research.

Results We present the Mobile Toolbox research platform and its use in conducting remote assessments measuring the constructs of executive function, language, memory, and processing speed. The suite of assessments includes: Flanker, Face-Name (FNAME), Memory for Sequence (MFS), Picture Sequence Memory (PSM), Vocabulary, Number Match, Spelling, and Dimensional Charge Card Sort (DCCS) tests.

Conclusions Given the COVID-19 global pandemic and its associated stay-at-home orders, it is now more important than ever that researchers have access to well-designed cognitive assessments that can be administered entirely remotely.

Authors/Disclosures
Sarah Pila PRESENTER	Sarah Pila has nothing to disclose.
	No disclosure on file
Sandra Weintraub, PhD, F�鶹��ýӳ�� (Northwestern Mesulam Center for Cognitive Neurology and Alzheimer'S Disease)	Dr. Weintraub has nothing to disclose.
Cindy Nowinski, MD PhD	The institution of Dr. Nowinski has received research support from National Institutes of Health.
Aaron Kaat	Aaron Kaat has received personal compensation for serving as an employee of Northwestern University. Aaron Kaat has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Kaat Psychometric and Statistic Consulting.
	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
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	No disclosure on file
	No disclosure on file
	No disclosure on file
Larsson Omberg	Larsson Omberg has nothing to disclose.
	No disclosure on file
	No disclosure on file
	No disclosure on file

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