Âé¶¹´«Ã½Ó³»­

Âé¶¹´«Ã½Ó³»­

Explore the latest content from across our publications

Log In

Forgot Password?
Create New Account

Loading... please wait

Abstract Details

Epilepsy in the Republic of Guinea: Social Determinants of Clinical Outcomes
Global Health and Neuroepidemiology
P9 - Poster Session 9 (12:00 PM-1:00 PM)
13-006
To analyze social determinants of the clinical outcomes of people living with epilepsy (PLWE) in Guinea.
Sub-Saharan Africa (SSA) is disproportionately burdened by epilepsy. Guinea is a low-income country in SSA with few healthcare resources. Limited research evaluates the social determinants of outcomes among PLWE in SSA.
Participants were prospectively recruited to Ignace Deen Teaching Hospital (Conakry) in 2018 and received structured interviews, electroencephalograms, and clinical consultations with free antiepileptic drugs (AEDs). A survey instrument exploring household assets as a measure of wealth was designed from previous surveys of microeconomics and health. Multivariate logistic regression models with fixed effects were fit to assess the impact of socioeconomic factors on self-reported (1) frequency of seizures in the past month, and (2) regular intake of AEDs. Participants were stratified by age group: children (<13 years), adolescents (13-21), and adults (>21).

Of 285 participants (mean age=19.5 years, age range 0.8-66 years; 129 female; 106 children, 72 adolescents, 107 adults), there was an average of 4.2 seizures in the prior month. 64% were regularly taking AEDs.

In models for each age stratum, higher seizure frequency in the past month was associated with: older age in adults (p=0.015); a head of household education less than high school level in adolescents and children (p=0.028; p=0.026); and being male (p=0.009) in children.

No variables predicted whether adults regularly took AEDs. Adolescents were more likely to take AEDs when they had a head of household with at least a high school education (p=0.004) and came from wealthier households (p=0.046). Boys were more likely to regularly take AEDs than girls (p=0.047).

The clinical presentations of children/adolescents were independently associated with the highest household educational level and wealth. Future interventions should target households with lower levels of education and wealth to help ensure optimized care of young PLWE in Guinea.

Authors/Disclosures
Dylan R. Rice
PRESENTER
Mr. Rice has nothing to disclose.
No disclosure on file
No disclosure on file
Andre Vogel (Massachusetts General Hospital) No disclosure on file
No disclosure on file
No disclosure on file
No disclosure on file
No disclosure on file
No disclosure on file
Farrah J. Mateen, MD, PhD, FÂé¶¹´«Ã½Ó³»­ (Northwestern University Department of Neurology) Dr. Mateen has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Amgen. Dr. Mateen has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Genentech. Dr. Mateen has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Novartis. The institution of Dr. Mateen has received research support from Genentech. The institution of Dr. Mateen has received research support from Amgen. The institution of Dr. Mateen has received research support from TG Therapeutics. Dr. Mateen has received intellectual property interests from a discovery or technology relating to health care.