The aim of this study is to identify which motor function (MF) impacts the depressive state in patients with MS (multiple sclerosis).

Participants included 26 participants (24 women / 2 men) with MS. Self-reported habit of physical activity by answering questions about engagement in systematized programs of physical exercise. Beck and HADS scales, walking functional capacity, muscular strength and balance were used to examine associations of motor function and depressive state in MS patients. Statistical analyses were performed using descriptive statistics, Spearman’s correlation coefficient test and Fisher’s exact test.

All MS patients had a RRMS disease course with a short disease duration and mild level of disability based on EDSS scores. Spearman coefficients between HADS-D, BDI and data from demographic, clinical and motor function significant results : NHPT,(HADS-D : p=0.23 / BDI : p=0.04) ; Balance – COP cm/s (HADS-D : p=0.004 / BDI : p=0.007) ; RPE, slope :  (HADS-D : p=0.24 / BDI : p=0.03).

The MF measurement as shown by the results of this study that describe the mobility condition and have a significant influence on the depression status of MS patients.