Abstract Details

Title Prevalence of Cardiovascular Diseases and Vascular Risk Factors in Patients with History of Epilepsy/Seizures

Topic Epilepsy/Clinical Neurophysiology (EEG)

Presentation(s) P7 - Poster Session 7 (5:30 PM-6:30 PM)

Poster/Presentation
Number 12-011

Objective To describe the prevalence of common cardiovascular diseases and risk factors in patients with history of epilepsy/seizures (E/S).

Background

Increased risk of new-onset seizures among stroke-free atrial fibrillation (AF) patients is well reported. Some reports also suggested a higher risk of AF and myocardial infarction in patients with epilepsy.

Design/Methods This study was conducted at King Abdullah University Hospital-Northern Jordan. All adults (> 18 years) with history of E/S between 2012 and 2018 were included. We calculated the prevalence of cardiovascular diseases and common vascular risk factors in this cohort and compared it to an age- and gender-matched cohort of patients who had no history of E/S (NON-E/S) but visited the neurology clinic during the same period.

Results

A total of 937 patients were included, mean age 47 ± 19.7 years (males 53.1%). 726 (77.5%) patients had history of E/S. Comparing E/S with NON-E/S patients, the prevalence of ischemic heart disease was 12.7% versus 9.5% (P= 0.21); AF was 5 % versus 0.9 % (P= 0.009); congestive heart failure was 3.9% versus 1.4% (P= 0.08); and ischemic stroke was 21.3% versus 9.5% (P< 0.001).

There was no significant difference between the E/S and NON-E/S patients in the prevalence of diabetes, hypertension, hyperlipidemia and smoking. Obesity (BMI>30) was higher in NON-ES patients (41.5% vs 24.4% (P= 0.009)).

Conclusions

This study suggests that some cardiovascular diseases such as AF and ischemic stroke are more prevalent in patients with epilepsy, emphasizing the importance of screening and vigilance for such conditions in these patients.

Note: another abstract (ID: 4805) titled “PREVALENCE OF PULMONARY DISEASES IN PATIENTS WITH EPILEPSY/SEIZURES” by my colleague, Dr. Abdel-Hameed Al-Mistarehi, was submitted to �鶹��ýӳ�� 2020 meeting on same cohort of patients with a different disease focus.

Authors/Disclosures
Khalid I. El-Salem, MD, F�鶹��ýӳ�� (Jordan University of Science and Technology) PRESENTER	Dr. El-Salem has nothing to disclose.
Ahmed M. Yassin, MD (Jordan University of Science and Technology)	Dr. Yassin has nothing to disclose.
Abdel-Hameed Al-Mistarehi (Jordan University of Sceince and Technology (JUST))	Mr. Al-Mistarehi has nothing to disclose.
Abdallah Almegdadi, MD	No disclosure on file
	No disclosure on file
Mohammad Jamil Ahmad, MD	Dr. Ahmad has nothing to disclose.
	No disclosure on file
	No disclosure on file
Sama Almasri, MBBS (UAMS)	Dr. Almasri has nothing to disclose.
	No disclosure on file
Belal A. Aldabbour, MD (Islamic University of Gaza)	Dr. Aldabbour has nothing to disclose.
Suha Aqaileh, Jr., MD (King Abdullah University Hospital)	No disclosure on file