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Abstract Details

Predicting DRS-2 total scores from the MoCA
Aging, Dementia, and Behavioral Neurology
P7 - Poster Session 7 (5:30 PM-6:30 PM)
10-002
Evaluate whether a brief cognitive screen (Montreal Cognitive Assessment [MoCA]) is predictive of a more comprehensive cognitive assessment (Dementia Rating Scale -2 [DRS-2]) in patients being evaluated for deep brain stimulation (DBS) surgery, in an effort to streamline their screening process.
Cognitive impairment can be one exclusionary criterion for DBS surgery, and the Total score on the DRS-2 has frequently been used as an indicator of cognitive functioning for these patients. However, the DRS-2 is time-consuming, and it would be helpful to know if scores on brief cognitive screening measures can predict the DRS-2 Total score.
In 46 patients being considered for DBS surgery (32 with PD, 9 with ET, 3 with dystonia, and 2 others), the DRS-2 Total score was predicted by the score on the MoCA, age, education, sex, and race via stepwise multiple linear regression.
n the first step,MoCA scores significantly predicted DRS-2 Total scores (R2 = 0.35, p < 0.001). In the second step, education significantly added to the prediction of DRS-2 Total (R2 = 0.41, p < 0.001). None of the other variables (race, sex, age) added variance to the prediction model. In the simplest model, adding 111(y intercept)to the MoCA yielded a good estimate of the DRS-2 Total score.
Such prediction equations can aid clinicians in evaluating patients for DBS surgery. Although considering the entire clinical presentation remains important,a rapid screening tool may aid in the identification of the most likely DBS candidates. Future studies might examine if other clinical variables improve the predictability of these cognitive scores.
Authors/Disclosures
Meghan Zorn, PA (University of Utah)
PRESENTER 		Ms. Zorn has nothing to disclose.
No disclosure on file
No disclosure on file
Camila Henriques De Aquino, MD (University of Calgary) No disclosure on file
No disclosure on file
Paolo M. Moretti, MD (University of Utah) The institution of Dr. Moretti has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Abbvie, Inc. The institution of an immediate family member of Dr. Moretti has received research support from NIH. The institution of an immediate family member of Dr. Moretti has received research support from VHA. The institution of an immediate family member of Dr. Moretti has received research support from DOD.