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Abstract Details

Acute Flaccid Myelitis in a Non-Pediatric Patient
General Neurology
P5 - Poster Session 5 (8:00 AM-9:00 AM)
6-002
To describe a case of acute flaccid myelitis (AFM) that presented in a non-pediatric patient, offering additional evidence of its presentation outside of the typical age demographic and adding further characterization to this emerging condition.
AFM is a condition causing acute onset flaccid limb weakness primarily in children. Correlations with certain viral illnesses have been found, however specific pathogenesis remains unknown. Of note is the the occurrence of outbreaks of AFM biennially and in association with Enterovirus outbreaks. A confirmed case of AFM is defined by the acute onset of flaccid limb weakness in combination with MRI showing spinal cord abnormalities largely restricted to the gray matter and spanning one or more spinal segments. Since the first described outbreak in 2014, a total of 574 cases have been confirmed by the Centers for Disease Control and Prevention. 
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A 21-year old female presented with progressive weakness provoking multiple falls, severe fatigue, headaches, and body aches following an upper respiratory illness. Deep tendon reflexes were absent, and cerebrospinal fluid (CSF) analysis was remarkable for lymphocytic pleocytosis and elevated protein. Magnetic resonance imaging (MRI) revealed T2 hyperintensity extending from C1-T2 predominantly involving the anterior horns. Weakness continued to increase before subtly improving over the course of a ten day hospital stay. Functional improvements have been achieved by the patient at one-year follow-up with intensive physical therapy. 
AFM should be included on the differential for the presentation of acute weakness in adults as well as pediatric patients. As the incidence of AFM continues to rise, awareness of the condition and prompt obtainment of specimens in suspected patients is crucial to aid in investigation.
Authors/Disclosures
Stephanie Kazi (USD Sanford School of Medicine)
PRESENTER 		No disclosure on file
Justin A. Persson, MD (Avera) No disclosure on file