Abstract Details

Title EEG reactivity predicts outcomes in cardiac arrest patients.

Topic Epilepsy/Clinical Neurophysiology (EEG)

Presentation(s) P5 - Poster Session 5 (8:00 AM-9:00 AM)

Poster/Presentation
Number 12-011

Objective To evaluate EEG reactivity (EEG-R) in prediction of outcomes and improvement in Neurological examination in post cardiac arrest patients.

Background The presence of EEG-R is linked to better odds of survival. However, there is a lack of studies using standardized methods for EEG-R and determining the survival outcomes and improvement of neurological examination in cardiac arrest patients. We instituted a protocol for EEG-R in these patients and assessed changes in their clinical examination.

Design/Methods We retrospectively reviewed our prospectively maintained EEG database for cardiac arrest patients over a 6 month period. EEG-R was assessed daily using a stepwise approach of verbal, photic, tactile and peripheral and central noxious stimulus as we have previously presented (Zubairi et al. �鶹��ýӳ��, 2018). EEG reactivity was determined by an Epileptologist uninvolved in the patient care. Patients neurological assessment data during hospitalization and cerebral performance category (CPC) scores at 3 months were collected. We analyzed our patient EEG-R using standard Fischer test and Chi square.

Results 61 cardiac patients (mean age 65years; 28M:22F) were included in this study. 43 patients had EEG-R data. EEG-R was significantly associated with the survival of the patients (11 vs 3) in comparison to patients who did not have EEG-R (8 vs 21); p=0.002. EEG-R was associated with command following during hospital stay (71% vs 0%); p: 0.0001. The mean CPC at discharge for patients having EEG-R was 3.21±0.51 vs 4.76±0.44 (p=0.0001) for patients with no EEG-R. The sensitivity of EEG-R for survival prediction was 58% and the specificity was 87% in our study. The sensitivity for 3 months good outcomes (CPC 3 or less) was 46% and specificity was 100%.

Conclusions

Absence of EEG-R is predictive of hospital survival as well as 3 months outcomes with high specificity.

Authors/Disclosures
Vikram Bhinder, MD (University of Toledo) PRESENTER	No disclosure on file
Stephen Hantus, MD (Cleveland Clinic)	Dr. Hantus has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eisai. Dr. Hantus has received personal compensation in the range of $0-$499 for serving as a Consultant for UCB.
Vineet Punia, MD (Cleveland Clinic)	Dr. Punia has nothing to disclose.
Christopher R. Newey, DO (Sanford Health)	Dr. Newey has nothing to disclose.