Abstract Details

Title Relationship of Sleep-Related Complaint Load to Quality of Life in Epilepsy

Topic Sleep

Presentation(s) P2 - Poster Session 2 (8:00 AM-9:00 AM)

Poster/Presentation
Number 5-001

Objective Our aim was to find a relationship between number of sleep-related complaints (SRC) and Health-related quality of life (HRQOL) in patients with epilepsy (PWE).

Background Sleep disorders have impact on both epilepsy disease severity and quality of life of patients. HRQOL is an important factor in management of PWE. Understanding this relationship could be very important in clinical practice for management of epilepsy with comorbid sleep disorders.

Design/Methods PWE and subjectively healthy controls were included into study as epilepsy (EG) and control (CG) groups. SRC were obtained through interviewing with special form. Interviewees were asked about 16 SRCs including insomnia, snoring, excessive daytime sleepiness, restlessness in legs, paralyzed awakenings, complex sleep behaviors, etc. For evaluation of HRQOL SF-36 questionnaire was used with its 8 domains (D): D1–physical functioning, D2–role-limitations due to physical health, D3–role-limitations due to emotional problems, D4–energy/fatigue, D5–emotional well-being, D6–social functioning, D7–pain, D8–general health. We used Spearman’s correlation method for statistical analysis.

Results We included 151 PWE (F=52.3%) and 130 controls (F=52.3%) in this study. Mean age was 35.2 and 33.6 years respectively. The Spearman's rho values for correlations between SRC number and SF-36 data in EG/CG were D1: -0.373/-0.208, D2: -0.408/-180, D3: -0.435/-0.181, D4: -0.475/-0.367, D5: -0.377/-0.346, D6: -0.377/-0.149, D7: -0.445/-0.275, D8: -0.435/-0.242 respectively. Overall, in EG we found negative correlations for all SF-36 domains (p<0.001), while in CG correlations were seen for D4 and D5 only, not influencing physical and social domains (p<0.05).

Conclusions

According to our data, there is higher correlation between SRC number and HRQOL in PWE compared to controls. It appears that SRC could play bigger role for HRQOL in PWE than in healthy individuals. Understanding this relationship can help in better management of PWE with sleep disorders.

Authors/Disclosures
Garik Yeganyan, MD (Gyumri Medical Center) PRESENTER	Dr. Yeganyan has nothing to disclose.
	No disclosure on file
	No disclosure on file
Samson Khachatryan, MD, PhD	Dr. Khachatryan has nothing to disclose.

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Abstract Details