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Abstract Details

Utility of Video EEG (VEEG) in the Assessment of Staring Spells (SS) in Children with Autism
Child Neurology and Developmental Neurology
P16 - Poster Session 16 (5:30 PM-6:30 PM)
5-013
To report on the utility of VEEG in children with autism and SS.
Patients with autism are known to have a higher prevalence of epileptic seizures and can also often have SS. Earlier published studies conclude that there is limited role for routine EEG in the characterization of SS in this population, however, utility of long-term video EEG has not been assessed.

We conducted a retrospective chart review of autistic children with VEEGs done at our institution during May 2010-May 2019 to characterize SS. EEG done prior to VEEG (pEEG) was divided into normal, with seizures, with focal epileptiform discharges (EDs) or with generalized EDs. SS clinical characterization prior to VEEG was recorded- complex partial seizure (CPS), absence seizure (AS) or behavioral. Frequency tables were generated. Chi-square analysis was performed to test for any significant association between pEEG result or diagnosis prior to VEEG characterization with VEEG characterization of SS.
Of 75 subjects with VEEG, 33 had events, 27 without and 6 with seizures. Of 27 children without seizures, 15 had normal EEGs, one had non-epileptiform abnormalities on EEG, 6 had generalized EDs and 5 had focal EDs. Of 42 subjects without events, 33 had normal EEGs, 8 had focal EDs and 1 had non-epileptiform EEG abnormalities. Seizures recorded on pEEG significantly predicted seizures on VEEG (p=0.04) while normal pEEG predicted a normal VEEG (p=0.02). SS characterization as CPS or AS prior to VEEG, significantly predicted similar characterization on VEEG (p=0.045).

VEEG proved useful in characterizing SS in almost half our subjects. However, VEEG may be superfluous in some subgroups as it may not help change the diagnosis for patients with a normal pEEG; those with seizures captured on pEEG and those with prior CPS or AS clinical characterization.
Authors/Disclosures

PRESENTER 		No disclosure on file
Stephen G. Jones, MD (Arkansas Children's Northwest, Pediatric Neurology) No disclosure on file
Kapil Arya, MBBS, DA, FAAP, FACNS, FÂ鶹´«Ã½Ó³»­ (UAMS - Pediatric Neurology) Dr. Arya has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Genentech. Dr. Arya has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novartis. Dr. Arya has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Scholar Rock.