Abstract Details

Title National Estimates Of Recurrent Intracranial Hemorrhage Among Patients With Unruptured Intracranial Aneurysms: Effect Of Treatment Modality

Topic Cerebrovascular Disease and Interventional Neurology

Presentation(s) P13 - Poster Session 13 (5:30 PM-6:30 PM)

Poster/Presentation
Number 4-010

Objective To determine the rates of recurrent intracranial hemorrhage related hospitalization within 3 months post-hospitalization for treatment of unruptured intracranial aneurysm in a nationwide cohort of patients treated for unruptured aneurysms.

Background The estimates of recurrent intracranial hemorrhage in the post-hospitalization period among patients treated for unruptured intracranial aneurysms are not available outside clinical trials (real-world experience).

Design/Methods We identified all readmissions related to new subarachnoid or intracerebral hemorrhages in the nationally representative data for all patients hospitalized for unruptured intracranial aneurysms using the Nationwide Readmissions Database (NRD) 2013 and 2014 who had undergone endovascular or surgical treatment. Cox proportional hazards analysis was used to assess the relative risk (RR) of recurrent intracranial hemorrhage for patients in treatment cohorts after adjusting for potential confounders. The survival was estimated for both treatment groups by using the Kaplan-Meier survival method.

Results A total of 11,696 patients with un-ruptured cerebral were treated with either endovascular (n = 7,035, 60.1%) or surgical treatment (n = 4,667; 39.9%).- The mean age (SD) of patients who underwent endovascular treatment was higher than those who underwent surgery (58.9 vs 56.1 years; p= <.0001). The estimated 3-month intracranial hemorrhage related hospitalization free survival was 99.5% and 99.0% in patients who underwent surgical and endovascular treatments, respectively (p= 0.08). After adjusting for age, and APDRG severity score, the RRs of recurrent any intracranial hemorrhage were similar with endovascular and surgical treatment (RR, 1.3; 95% confidence interval (CI), 0.6 -3.2 p= 0.50).

Conclusions Short-term rates of recurrent intracranial hemorrhage related hospitalization were low among patients with unruptured intracranial aneurysms and similar in two treatment modalities in real-world experience.

Authors/Disclosures
PRESENTER	No disclosure on file
Saqib A. Chaudhry, MD	Dr. Chaudhry has nothing to disclose.
Ameer Hassan, DO (Valley Baptist Medical Center)	Dr. Hassan has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Medtronic. Dr. Hassan has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Stryker. Dr. Hassan has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Penumbra. Dr. Hassan has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Cerenovus. Dr. Hassan has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Viz.ai. Dr. Hassan has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Genentech. Dr. Hassan has received research support from GE Healthcare.
Sairah Bashir, MD, F�鶹��ýӳ��	Dr. Bashir has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Medtronic .
	No disclosure on file
	No disclosure on file
Hamza I. Maqsood, MD (Dept of Neurology)	Dr. Qureshi has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for AstraZeneca.

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