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Abstract Details

Orthopedic Complications of Congenital Zika Syndrome May Predict Chronic Pain
Pain
P12 - Poster Session 12 (12:00 PM-1:00 PM)
6-006
This cohort study aimed to describe the orthopedic complications in children with microcephaly (MCP) related to Zika virus (ZIKV).
Orthopedic complication may be a predictor for chronic pain in cases of Congenital Zika Syndrome (CZS). Even though there is no model to explain the mechanisms of pain in CZS, it is well known on other diseases that there is a close relationship between orthopedic deformities and chronic pain.
We evaluated 36 children with CZS up to 17 months of age followed at a pediatric rehabilitation center in the northeast of Brazil. Cohort enrollment occurred with children born between January 2015 and May 2016. We assessed their social profiles and orthopedic findings.
Of the 36 cases, 25 were male. All of them lived in rural area. 25 had at least one congenital orthopedic alteration. Hip subluxation was the most common problem detected (n= 15); other lower limb abnormalities included knee subluxation (n=7), clubfoot (n=7); congenital vertical talus (n=4); plano-valgus foot (n=5). In relation to the upper limbs, 11 children presented with some shoulder and/or elbow abnormality and 16 had some alteration in the hand and/or on the wrist.
Orthopedic problems appear to be common in children with CZS and should be a focus of larger clinical studies. An initial orthopedic assessment may provide a better quality of life by helping children avoid chronic pain. Our results reinforce the link between rural living and the risk of CZS and the need to understand the effect offspring. These findings support the broad spectrum of clinical presentations among CZS cases. Our study may be used to better describe the CZS, its clinical outcomes and natural history.
Authors/Disclosures

PRESENTER 		No disclosure on file
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Tabata de Alcantara No disclosure on file