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Abstract Details

Simultaneous presentation of Neurocysticercosis and Giant Perivascular Spaces
Infectious Disease
P12 - Poster Session 12 (12:00 PM-1:00 PM)
13-004
Diagnostic sequelae of simultaneous Neurocysticercosis (NCC) intraparenchymal cystic lesions and giant perivascular spaces (PVSs).
Neurocysticercosis (NCC) is a cystic infection of the central nervous system (CNS) that can cause seizures, meningitis, encephalitis, and focal neurologic deficits. NCC commonly appears as ring-enhancing lesions with pericystic edema that often resolves into calcified nodules. The NCC radiographic findings can mimic benign and uncommon non-enhancing Virchow-Robin perivascular spaces (PVSs). A combination of NCC and PVSs is an extremely rare finding that may complicate diagnosis.
N/A

A 39-year old male immigrant from Mexico with no past medical history of seizure presented to the ED for concerns of head trauma secondary to assault. Patient reported only mild headache and facial bruising. Review of neurological history showed no cognitive dysfunction, weakness, numbness, or bowel or urinary incontinence. At presentation vitals were stable. Primary and secondary trauma survey was inconclusive.

Neurologic exam was grossly intact, no focal neurologic deficits were identified. CT head showed chronic multiple cystic lesions with calcifications consistent with NCC. MRI brain showed calcifications on SWIp alongside findings consistent with giant PVSs. Serum ELISA anti-cysticercosis antibodies were negative. Confirmatory Western-blot of anti-cysticercosis IgG was sent.

Based on history and imaging, the patient was diagnosed with NCC with radiographic presence of giant PVSs. Treatment regimen consisting of albendazole, praziquantel, and prednisone was given for 10 days.

Outcome: Treatment was stopped after patient showed clinical and radiographic improvement


NCC and PVSs have been reported in separate cases to differentiate infectious parenchymal disease from more benign processes. However, a rare combination of NCC and giant PVSs in the same case can lead to a diagnostic challenge.
Authors/Disclosures

PRESENTER
No disclosure on file
No disclosure on file