A total of 599 patients were included, 289 (48%) of which were readmitted (87 general, 60 epilepsy, 142 stroke). Across all services, readmitted patients had more than 1 hospital visit the year prior, a longer LOS, and greater medications at discharge, with hospital visits being statistically significant after adjusting for confounders. General Neurology service readmissions had more seizure as admitting disorder and had an ICU stay. In the stroke service, readmitted patients were older, had more specific comorbidities (hypertension, malignancy, dementia), had dysphagia or a tracheostomy/percutaneous endoscopic gastrostomy tube placement, and had a mRS of 4 or 5. Variables associated with epilepsy readmissions were greater than 8 seizures per month, prior VNS placement, and more total comorbidities.